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Moreover, microbial production of hydrogen sulfide by sulfur-reducing bacteria has been linked to enhanced host GSH production, suggesting that microbial antioxidative agents can regulate the host GPX4/GSH system, thereby further contributing to the protective effects [37, 38]

Duman RS, Aghajanian GK, Sanacora G, Krystal JH

Under physiological conditions, the BBB serves as a critical interface composed of endothelial cells connected by tight junction proteins, pericytes, and surrounding glial elements regulating the transport of molecules to the central nervous system

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