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Cholesterol gallstone susceptibility loci: a mouse map, candidate gene evaluation, and guide to human LITH genes

Further investigation has shown FOXO4 to inhibit the development of these harmful cells in animals, resulting in improved repair tissue quality

The dosage is 70-90mg/kg

Animals and housing Following laboratory animal welfare (3Rs: Replacement, Reduction, and Refinement) best practice [31], we acquired 13 adult female mice (C57BL/6 background) from another lab which were excess to experimental requirements, experimentally nave, and slated for euthanasia

Many patients notice improvement within 1-2 weeks, particularly reduced pain and improved mobility at injury sites