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In another study, oral supplementation of 50 mg/kg of glutathione led to an increase in the protein-bound fraction of plasma glutathione levels but did not impact the glutathione content in the blood cell or deproteinized plasma

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This variability complicates the comparison of results across studies and impairs the reliability of meta-analyses [558564]

Discussion Here, we present the first evidence of the physiological role of endogenous hepsin in redox homeostasis and its potential protective effect early after APAP exposure, which is crucial for mitigating liver injury

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