15, 1983 13 WO Patent No
In a comparative study, repeated exposure of human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates led to alterations in morphology, suppression of proliferation and induction of apoptosis, with changes in all three parameters greater in cells exposed to CS condensate [29]
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Nicotine is the drug component of cigarettes and is very addictive.[8] About half of cigarette smokers die of tobacco-related disease[9] and lose on average 14 years of life.[8] Cigarette use by pregnant women has also been shown to cause birth defects, including low birth weight, fetal abnormalities, and premature birth.[10] Second-hand smoke from cigarettes causes many of the same health problems as smoking, including cancer, [11][12][13][14] which has led to legislation and policy that has prohibited smoking in many workplaces and public areas
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