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Mechanism of Action: It works by promoting angiogenesis (the formation of new blood vessels), reducing inflammation, and enhancing tissue repair (Zhao et al., 2020)

In further embodiments, the tonicity agents are present in an amount as to provide a final osmolality of an otic formulation or composition of about 100 mOsm/kg to about 500 mOsm/kg, from about 200 mOsm/kg to about 400 mOsm/kg, from about 250 mOsm/kg to about 350 mOsm/kg or from about 280 mOsm/kg to about 320 mOsm/kg

It does not need to be refrigerated while sealed

Predicted performance of the MIRI coronagraphs

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