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Ni II /Co II - or Fe II -Sensing Riboswitches The NiCo riboswitch was originally discovered and functionally characterized in Clostridium botulinum and Erysipelotrichaceae bacterium (Eba) cultured in the presence of Co II

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characterized a mouse model of ALS with a mutant mtSOD1 gene with a Glycine to Alanine substitution (SOD1G93A) to clarify the etiology of the disease (Soares et al., 2023)