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[67] The CDC surveillance case definition for probable cases of severe pulmonary disease associated with e-cigarette use: [67] Using an e-cigarette ("vaping") or dabbing in 90 days before symptom onset AND [67] Pulmonary infiltrate, such as opacities on plain film chest radiograph or ground-glass opacities on chest computed tomography AND [67] Infection identified via culture or polymerase chain reaction, but clinical team believes this is not the sole cause of the underlying respiratory disease process OR minimum criteria to rule out pulmonary infection not met (testing not performed) and clinical team believes this is not the sole cause of the underlying respiratory disease process and [67] No evidence in medical record of alternative plausible diagnoses (e.g., cardiac, rheumatologic, or neoplastic process)

The nicotine pouch market is attracting aggressive competitors, and the gap between ZYNs premium positioning and lower-priced alternatives is being tested

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