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568,569 Deceased expression of astrocytic glutamate transporters was also detected in SOD1 G93A mice, 568,569 whereas transgenic overexpression of EAAT2 570 or pharmacological stimulation of its expression with riluzole 571,572 delayed progression of experimental APS

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18,19 Although heavy metal toxicities due to lead, mercury, and cadmium are generally considered rare in mainstream medicine, less well-recognized is that chronic accumulation that may not achieve classical acute toxicity thresholds may nevertheless contribute to adverse health effects