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Mitochondrial changes associated with glutathione deficiency

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For example, the mutation of a highly conserved serine residue in the MBL of monovalent metal specific regulators to a cysteine, based on its presence in divalent metal regulators, resulted in variants capable of sensing both Hg II as well as the monovalent coinage metals (Figure 24B)

Perilipin 1, a lipid droplet scaffold protein that coordinates interactions with ABHD5 and HSL Perilipin 1 (PLIN1), initially discovered by the group of Constantine Londos, is the major adipocyte perilipin/ADRP/TIP47 (PAT) protein (35) that functions as a scaffold to organized protein-protein interactions on the surface of LDs (36)