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These data suggest that while markers of fibrosis and autophagy are increased following liver-specific Gclc deletion, these are potentially due to the activation of NRF2

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Instead, metal coordination occurs through short linear motifs, where residues close in the sequence form a metal binding site

Overexpression of metallothionein in pancreatic beta-cells reduces streptozotocin-induced DNA damage and diabetes

The docking affinity was calculated as 6.3 0.75 kcal/mol, with a pKi of 1.36 0.55 M