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To enhance comprehensiveness, manual screening of reference lists from key articles and recent reviews was conducted to identify additional relevant studies not captured through database searches

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The review also noted the 2021 retrospective study comparing BPC-157 alone versus BPC-157 combined with TB-500 in knee injection protocols, where the combination was associated with improved outcomes described as the first directly comparative clinical observation of the Wolverine Stack pairing

Intercellular glutamate signaling in the nervous system and beyond