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Metabolites of a tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), in the urine of smokeless tobacco users: relationship of urinary biomarkers and oral leukoplakia

This finding supports previous evidence that, although awareness and acceptance of the health risks of smoking may not be a sufficient condition for quitting, it is likely a necessary one for most smokers and serves an important source of motivation

However, the harmful chemicals in tobacco smoke can disrupt hormone production

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Other user behaviors, like the number of daily cigarettes, can also impact overall consumption