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"Estimating the health impact of nicotine exposure by dissecting the effects of nicotine versus non-nicotine constituents of tobacco smoke: A multivariable Mendelian randomisation study"

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Additionally, older age may mean longer exposure to tobacco smoke and other carcinogens (cancer-causing substances), increasing the risk of developing lung cancer

40 If evidence-based methods are ineffective or the patient does not comply with them, e-cigarettes may be discussed

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