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The young WT HSCs harbor motifs for Pax7 (1e-2) while the induced regions in the aged WT HSCs harbor CTCF (1e-1965), ETV2 (1e-1063), ERG (1e-1032), FLI1 (1e-993), PU1 (1e-577), AP1 (activating protein-1, 1e-300), and IRF3 motifs (1e-131) (Fig

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