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Its substrate site-targeting mechanism inhibiting NNMT at the nicotinamide binding site provides selectivity over related methyltransferases and other enzymes in the NAD salvage pathway, making it a precise tool compound for studying NNMT-specific enzymatic activity in controlled laboratory systems
Some prefer mixing in the same syringe for fewer injections, while others administer separately to allow individual tracking
Retrieved August 10, 2014
Initial Loading Dose: At first, people get 1000 mcg every week for 4-8 weeks