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10.1186/s12931-021-01641-y Summary Keywords methotrexate, modified citrus pectin, galectin-3, hepatotoxicity, lung toxicity Citation Ismail R, Habib HA, Anter AF, Amin A and Heeba GH (2025) Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-B/TNF- and TGF- signaling pathways

Activation of Nrf2 and a subsequent induction of GCL have been reported for various oxidants and electrophiles such as DEM, H 2 O 2 , quinones, 4-hydroxynonenal, methyl mercury, arsenicals, and plasmonic gold nanoparticles (Zhang et al

a Includes 2 family practice physicians, 2 plastic surgeons, and 1 osteopath, OB-GYN, and primary care provider

Mechanism of Action of Epithalon Epithalon is a synthetic version of epithalamin, a peptide naturally produced by the pineal gland

Neuroimmunomodulation 32, 115