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Of the total adverse events reported, 37% were gastrointestinal in nature [207 events in 73 (77%) of 95 participants], most frequently nausea [67 events in 53 (56%) participants], vomiting [43 events in 23 (24%) participants], and dyspepsia [32 events in 27 (28%) participants]
However, its worth noting that although BPC-157 has been the subject of numerous preclinical publications, its currently unapproved for human consumption and can only be evaluated as a research compound within scientific settings
Often without connecting the two
Across the survodutide trials, investigators used multi-week dose-escalation phases 20 weeks in the obesity study and 24 weeks in the MASH study before reaching maintenance doses