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Similarly, melatonin receptor MT1 deficiency exacerbates -syn pathology and ferroptosis in PD models by disrupting the Sirt1/Nrf2/HO-1/GPX4 axis and promoting iron accumulation, whereas MT1 overexpression attenuates these effects (Lv et al., 2024)

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[37] [38] Chronic consumption of paracetamol is in many cases not of benefit, [25] and may result in abnormal liver function tests, and higher doses may lead to toxicity, including liver failure