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doi: 10.1101/gad.1529107 135 IsraelMSchwartzL

However, the increased complexity of dual agonism may also introduce new sources of variability related to the relative sensitivity to each receptor pathway

Studies conducted in mouse models of DMD have suggested that Receptor Grade IGF-1 LR3 and other IGF-1 derivatives may overcome the adverse impacts of Myostatin to protect muscle cells and prevent apoptosis