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Typical experimental endpoints include measures of collagen and extracellular matrix protein expression, cell migration rates, cytoskeletal organization, and transcriptional changes in genes related to tissue structure and repair, depending on the model

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combining such optical engineering with GSH-responsive agents (which modulate local thermosensitivity or ROS production) creates opportunities for multi-modal regimens that exploit both physical (light/heat) and chemical (redox) vulnerabilities in tumors [24]

Peris, E

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