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centrally, a harmful inability to drain venous blood adequately for a given cerebral blood inflow without raising venous pressures was resolved, evidencing rapid counteraction of such venous and intracranial hypertension [20,58,59,60,61,62]

Mice with homozygous null mutation for the most abundant glutathione peroxidase, GPx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide