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Analytical validation confirms above 99.8 percent purity assay content of 49.5 mg RT identification 0.994 spectrum 992 endotoxin below 0.001 EU per mg and no detectable heavy metals or microbial contamination

Because Krystexxa is given intravenously, it would be expected that the great majority of its use would be by rheumatologists rather than by internists or primary care physicians

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After defining signature peptides for target proteins, just unique peptide sequences were applied in PRM analysis