Glutathione S-transferases have been shown to be induced by a wide range of chemical agents (Ulmasov et al, 1995), wounding, heavy metals, ethylene, and ozone (Marrs, 1996)
Cheignon C, Tomas M, Bonnefont-Rousselot D, Faller P, Hureau C, Collin F
By reducing levels of these mediators, cold therapy creates conditions more favorable for tissue preservation
These antioxidants support glutathione recycling and enhance its effectiveness
For instance, the total NADP(H) is about 420 nmol/g wet weight in rat liver and 59% of total NADP(H) is found in mitochondria, and 30 nmol/g wet weight in skeletal muscle, 5,8 and the NADPH concentration in the cytosol is 3.1 0.3 and 37 2 M in the mitochondrial matrix in HeLa cells