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Like B12 shots, oral supplements are generally safe (4), even if you take more than the recommended 2.4 pg/mL per day

Jaul E, Barron J (2017) Age-related diseases and clinical and public health implications for the 85 years old and over population

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Given the essential role of astrocytes in the hippocampal neurogenic niche in the control of neurogenesis (Song et al., 2002), it is tempting to speculate that dynamic promoter methylation might regulate expression of these Fgfs and contribute to the regulation of adult hippocampal neurogenesis

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