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npj Metab Health Dis 3 , 26 (2025)

Lipids 2010;45:1127-38

To determine whether erastin induces growth inhibition in OC cells, TOV-21G, KOC-7C, CaOV3 and SKOV3ip1 cells were treated with erastin for 24 hours and cell viability was assayed using Premix WST-1 assay (Figure 3)

Other good sources include seafood, poultry, and whole grains, though selenium content can vary based on soil conditions where the food was grown

Furthermore, we observed an enhanced degradation of nucleotide bases, as reflected in lower levels of xanthosine 5-triphosphate and subsequent accumulation of purine (i.e., hypoxanthine, uric acid, 5-hydroxyisouric acid, allantoin) and pyrimidine (i.e., ureidosuccinic acid, N-acetylcytidine) catabolites