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These limitations do not invalidate preclinical findings but emphasize the need for human clinical trials with appropriate sample sizes, standardized protocols, and validated outcome measures before establishing clinical efficacy in human patients

Tirzepatide is the active ingredient in Zepbound, working as a dual GLP-1 and GIP receptor agonist to help regulate appetite, improve metabolism, and support weight loss

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Metabolic Benefits In addition to weight loss, semaglutide has demonstrated metabolic benefits that make it appealing for individuals with obesity-related health conditions