10.7417/T.2018.2050 8 ArdahM
These symptoms typically resolve as the body adapts to increased glutathione levels
Capitalizing on this insight, we designed DHA-N@M nanoreactors not only to intensify oxidative stress through GSH depletion and NO/ONOO - generation but also to modulate lipid metabolism via PUFA supplement, creating a coordinated therapeutic axis that potently enhances ferroptosis and tumor suppression
2000), stroke, and seizures (Horning et al
Besides, zinc is also involved in the inhibition of invasion and adhesion in malignant prostate cancer cell through several ways: strongly prevents the enzymatic activity of prostate-specific antigen (PSA) and suppresses the invasion of LNCaP cells, 360 reduces the expression of vascular endothelial growth factor (VEGF), 361 interleukin (IL)-6, IL-8, matrix metalloproteinase-9 (MMP9), intercellular adhesion molecule-1 (ICAM1), diminished the activity of urokinase-type plasminogen activator and aminopeptidase N (AP-N) 362 (Fig