Cellular Wellness ALA may support healthy cellular function and help protect cells from everyday oxidative stress
How distinct intracellular GSH pools are differentially controlled, how flux between compartments is coordinated, and how these dynamics influence commitment to apoptosis, ferroptosis, and cuproptosis remain incompletely understood
Chovancova B, Hudecova S, Lencesova L, Babula P, Rezuchova I, Penesova A, Grman M, Moravcik R, Zeman M, Krizanova O (2017) Melatonin-induced changes in cytosolic calcium might be responsible for apoptosis induction in tumour cells
Durand RE, Olive PL
These findings collectively highlight the multifaceted neuroprotective influence of astrocytic DJ-1 on DA neurons, extending from classical anti-inflammatory and antioxidant support to include the preservation of a key metabolic pathway that directly counters the execution of ferroptosis