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Combined with prior evidence that SESN2 deficiency exacerbates hepatic steatosis, SESN2/ mice are inferred to have more severe hepatic lipid accumulation, whereas exercise reduces serum TC, TG and fat mass in both WT and SESN2/ mice, suggesting exercise may alleviate lipid abnormalities via improving hepatic lipid metabolism [38]

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Stimulation of BODIPY-loaded RPE cells with Cys 2 starvation or with BSO/erastin treatment increased ROS generation as measured by increased rate of BODIPY oxidation (Fig

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However, advances in our understanding of anti-viral immunity, cross-reactivity, and molecular mechanisms of vaccine-induced immunity offer renewed hope