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Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c

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Shen Z, Cui T, Liu Y, Wu S, Han C, Li J

Biochim Biophys Acta 1969;192:560562

Mechanism of Action Dual B12 Form Synergy : Methylcobalamin and hydroxocobalamin work together through complementary absorption and utilization pathways, with methylcobalamin readily crossing cellular membranes while hydroxocobalamin serves as a stable storage form that converts to active cobalamine as needed