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Chronic wounds are typically covered with inflammatory exudates and biofilms 25 , which constitute a physicochemical barrier hindering the penetration of topical therapeutic agents into the underlying live tissues

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For general skin anti-aging, systemic subcutaneous injection at 1 to 2 mg/day combined with topical application achieves the best tissue-level collagen response

The study patients received the pill before clinically-indicated Tc99 m scans for cancer staging