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doi: 10.1038/ncomms10680 38 McNabFMayer-BarberKSherAWackAOGarraA

Int J Dermatol 2015;55(2):153-157

Some individuals use BPC-157 specifically for injury recovery, while others experiment with it for gastrointestinal symptoms or inflammatory conditions

However, despite its tolerability and safety, most studies on PA have been conducted in vitro or using rodent models

Although patients neutrophils exhibit a low reduced glutathione (GSH)/oxidised glutathione (GSSG) ratio and a higher total Nrf2 level, the DNA-binding activity of nuclear Nrf2 remained unchanged relative to healthy controls and had reduced expression of glutamate cysteine ligase catalytic (GCLC), and modifier (GCLM) subunit mRNAs, compared to periodontally healthy subjects neutrophils