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Drug Treatment In this study, we used FOXO4 D-Retro-Inverso peptide (FOXO4-DRI, NovoPro, Shanghai, China) and ABT-263 (Apexbio Technology, Houston, TX, United States) to selectively remove the senescent chondrocytes

These polyphenols also enhance melanocyte pigmentation by promoting TYR activity, a key enzyme in melanin biosynthesis, while simultaneously mitigating UV-induced damage 142

Under extreme iodine exposure, the thyroid gland may also exhibit aberrant expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its death receptor (DR)-5, resulting in follicular cell apoptosis

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