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Recent research studies indicated that nonphosphorylated CagAs C-terminus has a conserved motif that interacts with the host hepatocyte growth factor receptor to promote inflammation and cellular development by triggering the Akt signalling pathway, which in turn triggers NF-B and -catenin, according to recent studies

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However, depletion of another -KG-producing enzyme, PSAT1, but not GDH1 greatly reduced AMPK expression in IMR90 cells (Supplementary Fig

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