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Meanwhile, myeloid-cell specific GPX4 haploinsufficient mice presented with SLE-like manifestations such as spontaneous skin lesions and systemic damage, further validating that ferroptosis of neutrophils serves a critical role in the pathogenies of SLE

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Studies have shown TB-500 to be involved in: * Cell migration and differentiation * Angiogenesis * Anti-inflammatory processes * Muscle and soft tissue recovery Its wide tissue distribution in research subjects makes TB-500 a versatile candidate for regenerative studies.

Oyen WJ, Boerman OC, Storm G, van Bloois L, Koenders EB, Claessens RAMJ, et al