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In peripheral blood mononuclear cells (PBMCs), E627* (rs35744605), A843H (rs3747517), and I923V (rs35667974) were associated with protection against T1D by reducing type I IFN-associated gene transcription following stimulation with IFN or poly(I:C), a MDA5 agonist (106, 107)

Haematologica 93 (11), 17551758

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Van Dijk M, Van Dijk ADJ, Hsu V et al (2006) Information-driven protein-DNA docking using HADDOCK: it is a matter of flexibility