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This is because Fe II in the presence of even small amounts of H 2 O 2 results in the generation of the biomolecule-damaging hydroxyl radical (OH) via Fenton chemistry which becomes catalytic in the presence of cellular reductants, and catastrophic for cellular function

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Conclusion: Multimodal training is effective for multiclass Circle of Willis segmentation in stroke and can be used to unify imaging pipelines while improving performance