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Toxicological risks and human health implications of non-biodegradable nanomaterials Non-biodegradable nanomaterials like AgNPs, AuNPs, PtNPs, and FeO NPs are widely used in industrial, medical, and agricultural settings

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Genetic knockdown of DHFR decreases BH 4 levels and increases BH 2 levels, uncoupling eNOS and reducing NO production ( 4 ( Challenges Due to the lack of specific DHFR activators, there are no clinical studies that examined the possibility of stimulating its activity to increase NO availability