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Transferrin receptor is a specific ferroptosis marker
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Thus glutathione is perhaps uniquely positioned to not only provide cellular protection against oxidative and xenobiotic stress, but to also directly regulate cellular activity, including cell cycle control and induction of apoptosis in overly damaged cells
Next, the At LDOX protein was removed using an Amicon Ultra-4 device (10 kDa cut-off) (Merck Millipore) and the eluent was diluted with 1.375 vol of the same reaction buffer containing 82% H 2 18 O and incubated at 30 C, 1,200 rpm using a 3 mm shaking diameter to achieve 18 O equilibration