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For example, in cells expressing an active Rab37 mutant, knockdown of ATG5/7 not only reduces autophagic flux but also diminishes tissue inhibitor of metalloproteinase 1 secretion, leading to suppressed lung nodule formation and metastasis (68)

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P = 0.1043) or time to deproteinization (F 1,19 = 2.8008

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