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On the other hand, cancer cells also exhibit a significantly high consumption of glucose (the Warburg Effect) and lactate production

Although erastin demonstrates a potent inhibitory effect on Systems Xc-, its practical application in vivo is significantly hindered by its limited water solubility and metabolic instability

Mouse metabolism, mouse fat biology, and mouse dosing all differ from the human versions, and metabolic findings in rodents have a long history of not carrying over cleanly to people

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