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Similarly, bilayer wound dressings , such as asymmetric polycaprolactone (PCL)hydrogel constructs, demonstrate how spatially organized scaffold architectures can facilitate sequential control over hydration, antioxidant release, and tissue regeneration, reinforcing the value of spatiotemporal design principles in regenerative biomaterials [20]

We then statistically analyzed the intercristal distance within mitochondria in granulosa cells (Figure 4B) and found no significant difference in this parameter in the PmFstage granulosa cells present in the three groups (Figure 4G)

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