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Although PPV was considered an attractive strategy for PCa, and even after successful phase II trials, the phase III trial of 310 patients with mCRPC receiving docetaxel found no survival advantage over PBO (HR 1.04

Cells stained blue under an optical microscope were counted as positive cells, and DAPI counterstain was used to count the total cell number

Additionally, study participants with vitamin B12 deficiency and tinnitus reported a reduction in tinnitus symptom severity following therapy with vitamin B12 injections

The early results are encouraging