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doi:10.1038/nchembio.212, PMID: 19718041 Zahedi Avval F, Holmgren A (2009) Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for mammalian S phase ribonucleotide reductase

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Of interest, DHRS7 has been documented to establish intricate molecular-level interaction with core pathways (e.g., PI3K/AKT and MAPK) involved in tumorigenesis, which in turn profoundly affected key biological processes, such as cell proliferation, survival, and metastasis [16]