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Because of the enhanced bioavailability and decreased clearance of the nanoparticles, it is thought that a larger aspect ratio of the particles corresponds with increased cytotoxicity

Gastroenterology , 2004

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superoxide anion (O2), singlet oxygen radical (1O2), peroxyl radical (ROO), nitric oxide radical (NO) and lipid peroxy radical (LOO) as well as peroxynitrate (ONOO), trichloromethane (CHCl3) and hypochlorous acid (HOCl) which are not necessarily free radicals but have high tendency to generate free radicals

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