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As B12 is essential for the production of red blood cells and proper nervous system function, its deficiency can disrupt these processes and lead to symptoms like gastrointestinal discomfort and poor appetite, which may contribute to unintended weight loss

doi: 10.1007/s00018-019-03253-8 22 LeeDMoawadARMorielliTFernandezMCO'FlahertyC