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Doubling doses does not accelerate angiogenesis
The peptide interacts with the nitric oxide (NO) system, modulating vascular tone and cell signaling at the microenvironmental level to support the transition from the inflammatory phase to the proliferative phase of healing
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While a broader study, involving clinical trials, will be necessary to revise therapeutic protocol for nasal drug delivery, the present results illustrate the easy adaptability of our findings into clinical practice settings
Molecular Characteristics Complete Specifications: CAS Registry Number: NOT ASSIGNED (synthetic modified peptide) Molecular Weight: 431.40 Da (42 Da higher than Epitalon due to acetyl group) Molecular Formula: CHNO Amino Acid Sequence: N-Ac-Ala-Glu-Asp-Gly (acetylated AEDG) Modification: N-terminal acetylation (acetyl group: COCH) Peptide Classification: Synthetic modified tetrapeptide Appearance: White to off-white lyophilized powder Solubility: Water, bacteriostatic water, phosphate buffered saline The N-acetyl modification adds 42 Da to the molecular weight compared to unmodified Epitalon (390.35 Da)
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