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Therefore, we speculated that CBS is nonfunctional under supraphysiological cystine concentrations and investigated its function in a customized culture media containing cystine at a physiological concentration of 50 M or less

This mitochondrial failure is the direct biochemical driver of the profound, debilitating fatigue and post-exertional malaise (PEM) that patients experience after even minor physical or cognitive exertion

6gi) and prevented the accumulation of ophthalmic acid (Extended Data Fig

In planta expression screens of Phytophthora infestans RXLR effectors reveal diverse phenotypes, including activation of the Solanum bulbocastanum disease resistance protein Rpi-blb2