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In a model of primary sclerosing cholangitis (PSC), MSC-EVs reduced liver fibrosis, dampened immune cell infiltration, and suppressed NF-B activation, highlighting their capacity to modulate inflammation and fibrotic pathways [190]

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They designed a microfluidic device able to support the growth of patient-derived ISEMFs and ECs, demonstrating the response of the system to different physiological parameters, such as oxygen tension, cell density, growth factors

Circulation 146 , 16411643 (2022)