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Yet, advances in oral delivery, transdermal systems, and other innovative pathways are reshaping the way peptides can be used in medical and performance contexts

Studies have shown that AS-IV downregulates the expression of intestinal fibroblast growth factor 15, activates the liver farnesoid X receptor (FXR) signaling pathway, upregulates glucagon-like peptide-1, and reduces ceramide production, thereby modulating lipid synthesis processes that regulate cholesterol transport and optimize lipid metabolism in the liver (Zhai et al., 2022)

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